complications of gold sodium thiomalate therapy in rheumatoid arthritis

نویسندگان

بهزاد حیدری

heidari b ضیاءالدین نوروزی

noroozi z

چکیده

to determine the complications of gold sodium thiomalate therapy in rheumatoid arthritis (ra), 32 patients with active ra (27 female, 5 male) treated for a mean period of 28 ? 14 weeks were studied. from these patients, 62.5 (46-79) percent showed at least one drug reaction. pruritus was the most common complication occurred in 59 (42-76) percents, and was accompanied by skin rush in 37 (15-57) percents of cases. renal, mucosal and post-injection complication developed, each in 16 (3-29) and percents of patients. hematologic and pulmonary reaction occurred in 12.5 (1-24) and 9 (1-19) percents of cases respectively. drug reaction resulted to discontinuation of gold therapy in 19 (5-32) percents of patients. majority of drug reactions occurred during the first 15 weeks of therapy. in comparison to reports coming from other studies, drug reactions in iranian patients were more frequent but less severe.

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

ADVERSE REACTIONS OF GOLD SODIUM THIOMALATE IN RHEUMATOID ARTHRI TIS PATIENTS IN SOUTHERN IRAN

To confirm the side-effects of gold sodium thiomalate (GSTM), we carried out a retrospective study examining 102 consecutive patients with rheumatoid arthritis attending the Rheumatology Unit of Hafez Hospital, Shiraz, Iran, in whom GSTM was initiated between 1983-1989. Only patients with classical or definite RA (ARA criteria) we(e included in this study. Patients were categorized as havi...

متن کامل

[Gold therapy in rheumatoid arthritis].

During the period 1971-1979, 114 patients with rheumatoid arthritis attending the arthritis clinics at Groote Schuur Hospital and Princess Alice Orthopaedic Hospital were treated with gold sodium aurothiomalate (Myocrisin). Data obtained from 104 completed protocols showed that 70 patients (67,3%) benefited from chrysotherapy. Forty of these patients went into complete remission. Therapy was di...

متن کامل

adverse reactions of gold sodium thiomalate in rheumatoid arthri tis patients in southern iran

to confirm the side-effects of gold sodium thiomalate (gstm), we carried out a retrospective study examining 102 consecutive patients with rheumatoid arthritis attending the rheumatology unit of hafez hospital, shiraz, iran, in whom gstm was initiated between 1983-1989. only patients with classical or definite ra (ara criteria) we(e included in this study. patients were categorized as having de...

متن کامل

Rheumatoid Arthritis and Gold Salts Therapy

IT is unfortunate that, in spite of the enormous amount of work that has been done in recent years on chronic arthritis, there is but little agreement as to what constitutes Rheumatoid Arthritis. Lawford Knaggs, in a report on the Strangeways Collection of rheumatoid joints in the museum of the Roval College of Surgeons, states that he was unprepared for the frequency witlh wihichi some of the ...

متن کامل

منابع من

با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید


عنوان ژورنال:
مجله دانشکده پزشکی دانشگاه علوم پزشکی تهران

جلد ۵۹، شماره ۱، صفحات ۸۱-۸۵

کلمات کلیدی

میزبانی شده توسط پلتفرم ابری doprax.com

copyright © 2015-2023